Mpox is a rare disease caused by infection with the monkeypox virus. Mpox virus is part of the same family of viruses as variola virus, the virus that causes smallpox. Mpox symptoms are similar to smallpox symptoms, but milder, and Mpox is rarely fatal. Mpox is not related to chickenpox.
Mpox was discovered in 1958 when two outbreaks of a pox-like disease occurred in colonies of monkeys kept for research.
The first human case of Mpox was recorded in 1970. Prior to the 2022 outbreak, Mpox had been reported in people in several central and western African countries. Previously, almost all Mpox cases in people outside of Africa were linked to international travel to countries where the disease commonly occurs or through imported animals. These cases occurred on multiple continents.
Mpox spreads in different ways. The virus can spread from person-to-person through:
It’s also possible for people to get Mpox from infected animals, either by being scratched or bitten by the animal or by preparing or eating meat or using products from an infected animal.
Mpox can spread from the time symptoms start until the rash has fully healed and a fresh layer of skin has formed. The illness typically lasts 2-4 weeks. People who do not have Mpox symptoms cannot spread the virus to others. At this time, it is not known if Mpox can spread through semen or vaginal fluids.
Mpox appears to be spreading now among some sexual and social networks of gay and bisexual men and other men who have sex with men (MSM). However, there is no such thing as a gay disease. Viruses and bacteria can and do infect anyone regardless of sexual orientation. It is also not a sexually transmitted infection. Instead, it is spread through close contact, as previously described. Anyone can get Mpox, including heterosexual people, women, transgender and nonbinary people, and others. It is important not to stereotype gay and bisexual men as bearers of disease. Gay and bisexual men already experience significant stigma and prejudice and are vulnerable to discrimination and violence victimization.
Stigma about gay and bisexual people, including laws criminalizing homosexuality and same-sex behavior which still exist in many countries, may cause men who have sex with men to fear disclosing their same-sex behavior. This may also make them reluctant to disclose that they are part of social and sexual networks that are disproportionately affected by the current outbreak, making prevention of the spread of monkeypox more difficult. The public health response to this outbreak of Mpox should not be allowed to exacerbate homophobia and the scapegoating of gay and bisexual men.
Take the following steps to prevent getting/spreading Mpox:
If you are sick with Mpox:
CDC recommends vaccination for people who have been exposed to Mpox and people who are at higher risk of being exposed to Mpox, including:
The CDC advises that people who have been exposed to Mpox be given the vaccine to prevent them from developing the disease. This is called post-exposure prophylaxis or PEP. PEP is most effective at preventing Mpox if the vaccine is administered within 4 days of exposure. If given between 4–14 days after the date of exposure, vaccination may help reduce symptoms, but may not prevent the infection from developing.
At this time, the JYNNEOS vaccine is being prioritized for the following groups:
Post-Exposure Prophylaxis (PEP) for known close contacts of Mpox cases who are identified by public health via case investigation, contact tracing, and risk exposure assessments.
Post-Exposure Prophylaxis (PEP)++ for individuals with certain risk factors who are more likely to have been recently exposed to Mpox even if they have not had documented exposure to someone with confirmed Mpox, such as people who attended an event or venue where there was known Mpox exposure.
Pre-Exposure Prophylaxis (PrEP) for individuals at occupational risk of Mpox according to Advisory Committee on Immunization Practices (ACIP) guidance, including: laboratory workers who perform Mpox testing, and clinical and public health workers who collect Mpox specimens.
California Department of Public Health
Harm-reduction messaging on how to lower chances of getting Mpox during Pride events (CDC)
Building Healthy Online Communities Resources, including Health Alerts in English and Spanish
Mpox: Get the Facts Flyer (CDC)
Mpox & Safer-sex: English and Spanish
Mpox & Pride: Know Before You Go — Recorded Webinar (InterPride)
What Gay & Bisexual Men Need to Know About Mpox in English and Spanish (CDPH, Gay Sexuality and Social Policy Initiative, and Los Angeles LGBT Center). Also available in nine languages here.
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